Asymmetric catalysis in intramolecular cyclopropanation
β Scribed by Koskinen, Ari M. P.; Hassila, Heikki
- Book ID
- 127158412
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 261 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Optically active Co(II)-salen complexes (5 and 7) were found to catalyze highly enantioselective intramolecular cyclopropanation of 2-alkenyl a-diazoacetates in the presence of N-methylimidazole under high substrate concentration.
## Abstract We have examined the catalytic asymmetric intramolecular cyclopropanation (IMCP) reactions of 5βarylβ1βdiazoβ1βmesitylsulfonylβ5βhexenβ2βones, and found that the substituent of the 5βaryl group dramatically changes the enantioselectivity. That is, no enantioselectivity was observed when