Co(II)–salen-catalyzed asymmetric intramolecular cyclopropanation

✍ Scribed by Tatsuya Uchida; Biswajit Saha; Tsutomu Katsuki

• Book ID: 104230292
• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 69 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)00218-0

✦ Synopsis

Optically active Co(II)-salen complexes (5 and 7) were found to catalyze highly enantioselective intramolecular cyclopropanation of 2-alkenyl a-diazoacetates in the presence of N-methylimidazole under high substrate concentration.