Asymmetric and ‘anti’-Selective Aldolisations of Acetates and Propionates. Preliminary Communication
✍ Scribed by Wolfgang Oppolzer; José Marco-Contelles
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- German
- Weight
- 283 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0018-019X
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## Abstract Using the readily accessible chiral auxiliaries **1**–**3** the sulfonamide‐shielded __O__‐silylated esters **5** underwent π‐face‐selective α‐acetoxylation on successive treatment with Pb(OAc)~4~ and NEt~3~ HF to give after recrystallization α‐acetoxy ester **6** in 55–67% yields and i
## Abstract The hydroformylation of α‐[^2^H]‐styrene in the presence of an asymmetric rhodium‐catalyst afforded two optically active isomeric aldehydes. The origin of the asymmetric induction is discussed on the basis of the chirality and the optical purity of the two products.
## Abstract [(−) (__R__)‐1,2‐bis (Diphenylphosphino)‐1‐phenylethane]nickel (II) chloride was found to catalyze the asymmetric alkylation of some chiral and achiral allylic alcohols with __Grignard__ reagents, leading to the formation of optically active olefins. Enantiomer discrimination of the sub
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