Nickel-catalyzed Asymmetric Alkylation of Some Chiral and Achiral Allylic Alcohols. Preliminary communication

✍ Scribed by Giambattista Consiglio; Franco Morandini; Oreste Piccolo

• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: German
• Weight: 207 KB
• Volume: 63
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19800630427

✦ Synopsis

Abstract

[(−) (R)‐1,2‐bis (Diphenylphosphino)‐1‐phenylethane]nickel (II) chloride was found to catalyze the asymmetric alkylation of some chiral and achiral allylic alcohols with Grignard reagents, leading to the formation of optically active olefins. Enantiomer discrimination of the substrate takes place in the alkylation of chiral allylic alcohols.