Synthesis of chiral acetic acids by a si
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Peter F. Leadlay; Shaun Greer
📂
Article
📅
1982
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Elsevier Science
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English
⚖ 335 KB
A simple procedure for the synthesis of chiral acetic acids has been developed. The key step is an enzymatic exchange reaction which introduces 'H from 'H-labeled water into ethane I ,2diol. The method involves no resolution of racemic intermediates and the products are of high specific radioactivit