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Asymmetric acetalization: a simple method for the synthesis of chiral a-monosubstituted cyclopentanones

✍ Scribed by Nishida, Mayumi; Nakaoka, Kazuyo; Ono, Shizuka; Yonemitsu, Osamu; Nishida, Atsushi; Kawahara, Norio; Takayanagi, Hiroaki


Book ID
127074428
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
258 KB
Volume
58
Category
Article
ISSN
0022-3263

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Synthesis of chiral acetic acids by a si
✍ Peter F. Leadlay; Shaun Greer 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 335 KB

A simple procedure for the synthesis of chiral acetic acids has been developed. The key step is an enzymatic exchange reaction which introduces 'H from 'H-labeled water into ethane I ,2diol. The method involves no resolution of racemic intermediates and the products are of high specific radioactivit