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Asymmetric [2+2] photocycloaddition of cycloalkenone–cyclodextrin complexes to ethylene

✍ Scribed by Akinori Furutani; Kyoshige Katayama; Yukihiro Uesima; Mikihiko Ogura; Yoshito Tobe; Hideo Kurosawa; Ken Tsutsumi; Tsumoru Morimoto; Kiyomi Kakiuchi


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
114 KB
Volume
18
Category
Article
ISSN
0899-0042

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Asymmetric 1,4-addition of phenylboronic
✍ Yoshiaki Takaya; Masamichi Ogasawara; Tamio Hayashi 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB 👁 2 views

Reaction of 2-cyclohexenone with phenylboronic acid in the presence of 3 mol% of a rhodium(I)/(S)-binap catalyst in dioxane/H2O (10/1) at 100 degrees C proceeded with high enantioselectivity to give a high yield of (S)-3-phenylcyclohexanone of up to 99% ee. The high enantioselectivity was achieved b