Astroglia induce neurogenesis from adult neural stem cells
β Scribed by Song, Hongjun; Stevens, Charles F.; Gage, Fred H.
- Book ID
- 109803490
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 566 KB
- Volume
- 417
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/417039a
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## Abstract The prospect of using embryonic stem cell (ESC)βderived neural progenitors and neurons to treat neurological disorders has led to great interest in defining the conditions that guide the differentiation of ESCs, and more recently induced pluripotent stem cells (iPSCs), into neural stem
Neural stem cells (NSCs) are the self-renewing, multipotent cells that generate neurons, astrocytes, and oligodendrocytes in the nervous system (Fig. 1a). Over the past decades, the confirmation that neurogenesis occurs in discrete areas of the adult brain and that NSCs reside in the adult brain has