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Astrocyte-specific heme oxygenase-1 hyperexpression attenuates heme-mediated oxidative injury

โœ Scribed by Luna Benvenisti-Zarom; Raymond F. Regan

Book ID
113812141
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
869 KB
Volume
26
Category
Article
ISSN
0969-9961

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## Abstract Hemin, the oxidized form of heme, is released from hemoglobin after CNS hemorrhage and may contribute to injury to surrounding tissue. The heme oxygenase (HO) enzymes catalyze the breakdown of hemin to biliverdin, carbon monoxide, and ferric iron. Although HOโ€2, the isoform expressed pr