Astro plenary: Interfraction interval is a major determinant of late effects, with hyperfractionated radiation therapy of carcinomas of upper respiratory and digestive tracts: Results from radiation therapy oncology group protocol 8313

interruptions adversely affect local con

interruptions adversely affect local control and survival with hyperfractionated radiation therapy of carcinomas of the upper respiratory and digestive tracts new evidence for accelerated proliferation from radiation therapy oncology group protocol 8313

✍ James D. Cox; Thomas F. Pajak; Victor A. Marcial; Lawrence Coia; Mohammed Mohiud 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 474 KB 👁 2 views

Hyperfractionated radiation therapy (HFX) attempts to overcome tumor proliferation during treatment by permitting higher total doses in the same overall time as standard fractionation. Whereas interruptions, including splits, reduce local control with standard fractionation in carcinoma of the upper