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Associations of insulin-like growth factor binding protein-3 gene polymorphisms with IGF-I activity and lipid parameters in adolescents

✍ Scribed by Mong, J L Y; Ng, M C Y; Guldan, G S; Tam, C H T; Lee, H M; Ma, R C W; So, W Y; Wong, G W K; Kong, A P S; Chan, J C N


Book ID
109866439
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
354 KB
Volume
33
Category
Article
ISSN
1476-5497

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## Abstract While extracellular acidification within solid tumors is well‐documented, how reduced pH impacts regulation of insulin‐like growth factor‐I (IGF‐I) has not been studied extensively. Because IGF‐I receptor binding is affected by IGF binding proteins (IGFBPs), we examined how pH impacted