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Associations of insulin-like growth factor and insulin-like growth factor binding protein-3 with mortality in women with breast cancer

✍ Scribed by Catherine Duggan; Ching-Yun Wang; Marian L. Neuhouser; Liren Xiao; Ashley Wilder Smith; Kerryn W. Reding; Richard N. Baumgartner; Kathy B. Baumgartner; Leslie Bernstein; Rachel Ballard-Barbash; Anne McTiernan

Book ID
115556530
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
358 KB
Volume
132
Category
Article
ISSN
0020-7136

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Insulin-like growth factors (IGFs) are potent mitogens involved in the regulation of cell proliferation and apoptosis. The action of IGFs is mediated through a specific cell membrane receptor (IGF-IR), and the interactions between IGFs and this receptor are regulated by IGF-binding proteins (IGFBPs)