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Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms

✍ Scribed by Halmai, Zsuzsa; Dome, Peter; Vereczkei, Andrea; Abdul-Rahman, Omar; Szekely, Anna; Gonda, Xenia; Faludi, Gabor; Sasvari-Szekely, Maria; Nemoda, Zsofia


Book ID
121202467
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
247 KB
Volume
150
Category
Article
ISSN
0165-0327

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## Abstract The P2RX7 gene (coding for P2X7 purinergic receptor) has been suggested as a novel candidate gene for major depressive disorder (MDD) and bipolar disorder (BPD). The proposed risk allele (G‐allele) of the rs2230912 polymorphism results in an amino acid change at the 460th position, mark