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P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients

✍ Scribed by Geza Nagy; Zsolt Ronai; Aniko Somogyi; Maria Sasvari-Szekely; Omar Abdul Rahman; Attila Mate; Timea Varga; Zsofia Nemoda


Book ID
116841411
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
196 KB
Volume
32
Category
Article
ISSN
0278-5846

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## Abstract The P2RX7 gene (coding for P2X7 purinergic receptor) has been suggested as a novel candidate gene for major depressive disorder (MDD) and bipolar disorder (BPD). The proposed risk allele (G‐allele) of the rs2230912 polymorphism results in an amino acid change at the 460th position, mark