A statistical model that uses an iterative maximum likelihood estimation procedure is proposed for measuring and testing the association between polymorhphic genetic markers and quantitative traits in human pedigrees, after adjusting for covariates such as age and sex. The model allows the quantitat
β¦ LIBER β¦
Association test between haplotypes and longitudinal traits in complex pedigrees
β Scribed by Q. Wang; D. Yu; Y. Pan
- Book ID
- 108900213
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 190 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0931-2668
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## Abstract With the increasing availability of genetic data, several SNPs in a candidate gene can be combined into haplotypes to test for association with a quantitative trait. When the number of SNPs increases, the number of haplotypes can become very large and there is a need to group them toget
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