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Association study of schizophrenia among Indian families

✍ Scribed by Prasad, S.; Deshpande, S.N.; Bhatia, T.; Wood, J.; Nimgaonkar, V.L.; Thelma, B.K.

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 9 KB
Volume: 88
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19990820)88:4<298::aid-ajmg3>3.0.co;2-a

No coin nor oath required. For personal study only.

✦ Synopsis

A putative association of schizophrenia with a Msc I restriction fragment length polymorphism at the dopamine D3 receptor gene locus (DRD3) was tested among Indian families, using haplotype relative risk analysis and the transmission disequilibrium test (n=66 families and 58 sets of transmissions, respectively). A significant association either with homozygosity or with allele 1 at the biallelic polymporphism could not be detected. Am.

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