## Abstract ## Background Previous studies have suggested a role for transforming growth factor (TGF) β and its receptor in thoracic aortic aneurysm, but their role in abdominal aortic aneurysm (AAA) is unknown. This study examined the possible association between TGF-β receptor 1 and 2 (TGFBR-1 a
Association studies of transforming growth factor-β1 and Alzheimer's disease
✍ Scribed by M.R. Dickson; R.T. Perry; H. Wiener; R.C.P. Go
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 69 KB
- Volume
- 139B
- Category
- Article
- ISSN
- 1552-4841
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## Abstract Transforming growth factor‐β (TGF‐β), a multifunctional cytokine, has been widely suggested to play a role in the pathogenesis of Alzheimer's disease. Supporting this, levels of TGF‐β are elevated in the cerebrospinal fluid, sera, and brain of patients with Alzheimer's disease. Since TG
Transforming growth factor-b (TGF-b) plays a central role in a wide array of cellular functions including control of cell growth and differentiation, embryonic development, wound healing, angiogenesis, and immune regulation. In the gastrointestinal tract, TGF-b can either promote or suppress inflamm