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Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease

✍ Scribed by Petra Nowotny; Sarah Bertelsen; Anthony L. Hinrichs; John S.K. Kauwe; Kevin Mayo; Sarah Jacquart; John C. Morris; Alison Goate

Book ID
116769553
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
187 KB
Volume
419
Category
Article
ISSN
0304-3940

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✍ Petra Nowotny; Xavier Simcock; Sarah Bertelsen; Anthony L. Hinrichs; John S.K. K πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 134 KB πŸ‘ 2 views

## Abstract Linkage studies have suggested a susceptibility locus for late‐onset Alzheimer's disease (LOAD) on chromosome 21. A functional candidate gene in this region is the β‐amyloid precursor protein (APP) gene. Previously, coding mutations in APP have been associated with early onset Alzheimer