✦ LIBER ✦

Association of tumor satellite distance with prognosis and contralateral neck recurrence of tongue squamous cell carcinoma

✍ Scribed by Tsung-Lin Yang; Cheng-Ping Wang; Jenq-Yuh Ko; Chih-Feng Lin; Pei-Jen Lou

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 213 KB
Volume: 30
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.20758

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background

The margin status is an important prognosticator for the survival of patients with tongue cancer. Although a positive margin is associated with a poor prognosis, those with clear margins do not always have good clinical outcomes.

Methods

We investigated the margin status, pattern of tumor invasion (POI), and tumor satellite distance (TSD) in 119 freshly treated tongue cancers and assessed their association with the characteristics and clinical outcomes.

Results

A close or clear margin and POI were not associated with overall survival. Tumor satellites occurred in 92% of tumors and were significantly associated with betel nut exposure. Patients with TSD ≤0.5 mm had significantly better overall survival. Patients with TSD >0.5 mm had a higher incidence of local recurrence, shorter intervals to neck recurrence, and a higher propensity to contralateral or bilateral cervical nodal metastasis.

Conclusion

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