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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

✍ Scribed by Ueda, Hironori; Howson, Joanna M. M.; Esposito, Laura; Heward, Joanne; Snook, Hywel; Chamberlain, Giselle; Rainbow, Daniel B.; Hunter, Kara M. D.; Smith, Annabel N.; Di Genova, Gianfranco


Book ID
109891065
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
301 KB
Volume
423
Category
Article
ISSN
0028-0836

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The immune system is a delicately balanced network of interacting cells. In recent years, the concept of immune regulation/suppression has been firmly established, and both natural and induced regulatory cells play vital roles in protection from autoimmune disease. Recent work has revealed the diver