Association of the microsatellite in the 3' untranslated region of theCD154gene with rheumatoid arthritis in females from a Spanish cohort: a case-control study
✍ Scribed by Trinidad Martin-Donaire, Ignacio Losada-Fernandez…
- Book ID
- 120706555
- Publisher
- BioMed Central
- Year
- 2007
- Tongue
- English
- Weight
- 378 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar2288
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## Abstract ## Objective The single‐nucleotide polymorphism (SNP) rs11761231 on chromosome 7q has been reported to be sexually dimorphic marker for rheumatoid arthritis (RA) susceptibility in a British population. We sought to replicate this finding and to better characterize susceptibility allele
## Abstract ## Objective Cytotoxic T lymphocyte–associated antigen 4 (CTLA‐4) is a negative regulator of T cells and is, therefore, a strong candidate susceptibility gene for T cell–mediated autoimmune diseases. The association of CTLA‐4 single‐nucleotide polymorphisms (SNPs) with rheumatoid arthr