## Abstract ## Objective Cytotoxic T lymphocyte–associated antigen 4 (CTLA‐4) is a negative regulator of T cells and is, therefore, a strong candidate susceptibility gene for T cell–mediated autoimmune diseases. The association of CTLA‐4 single‐nucleotide polymorphisms (SNPs) with rheumatoid arthr
✦ LIBER ✦
No evidence of association of the KLF12 gene with rheumatoid arthritis in Spanish and Dutch cohorts and a meta-analysis of published data
✍ Scribed by Mercedes García-Bermúdez; Raquel López-Mejias; Luis Rodriguez-Rodriguez; Benjamín Fernández-Gutierrez; Antonio García; Enrique Raya; Ana M. Ortiz; Marieke J.H. Coenen; Piet L.C.M. van Riel; Timothy R.D.J. Radstake; Miguel A. González-Gay; Javier Martín
- Book ID
- 116533127
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 459 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0198-8859
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## Abstract ## Objective The objective of this individual patient data (IPD) meta‐analysis was to examine the relationship of rheumatoid nodules to the HLA–DRB1 shared epitope (SE) and to individual SE genotypes. ## Methods English‐language studies that enrolled adult non‐Hispanic Caucasian pati