## 817 ated with increased risk for AD, at least in the Korean population. Nevertheless, it cannot be excluded that the association between IL-1A (-889) C/T polymorphism and AD observed in previous studies might be the result of linkage disequilibrium with a yet unidentified gene on chromosome 2.
Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population
β Scribed by Brown, Abraham M. ;Gordon, Derek ;Lee, Hsinhwa ;Caudy, Michael ;Hardy, John ;Haroutunian, Vahram ;Blass, John P.
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 99 KB
- Volume
- 131B
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The gene coding for urokinaseβplasminogen activator (PLAU) is a strong biological and positional candidate gene for Alzheimer's disease (AD). Previously some studies have examined the role of common variation in the PLAU gene with AD risk but the results have been inconsistent and this
## Abstract Accumulating evidence indicates that the heparanβsulfateβproteoglycan (perlecan, HSPG2), as well as other specific proteoglycans, are involved in amyloidogenesis and tau aggregation in Alzheimer's disease (AD). Moreover, the HSPG2 is located on chromosome 1p36, a region of linkage to la
It is now commonly known that possession of one of the three common alleles of the apolipoprotein E (APOE) gene (allele epsilon 4) confers an increased risk for both familial and sporadic Alzheimer's disease (AD), and that this risk is dose-dependent. Other genes that may play a role in AD, either t