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Association of renin–angiotensin system gene polymorphisms with antihypertensive responses to angiotensin-converting enzyme inhibition or angiotensin receptor blockade

✍ Scribed by Stergiou, G S; Efstathiou, S P; Inglis, G C; Connell, J M C; McInnes, G T; Mountokalakis, T D

Book ID: 110048885
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 70 KB
Volume: 19
Category: Article
ISSN: 0950-9240
DOI: 10.1038/sj.jhh.1001918

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A recent Japanese study on the angiotensin I converting enzyme gene (ACE) insertion/ deletion polymorphism reported that both the D allele (P < 0.02) and the DD genotype (P < 0.002) were significantly more frequent in affective disorder cases than in controls [Arinami et al., 1996: Biol Psychiatry 4