Association of human herpesvirus 6 reactivation with the flaring and severity of drug-induced hypersensitivity syndrome
โ Scribed by M. Tohyama; K. Hashimoto; M. Yasukawa; H. Kimura; T. Horikawa; K. Nakajima; Y. Urano; K. Matsumoto; M. Iijima; N.H. Shear
- Book ID
- 108669659
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 132 KB
- Volume
- 157
- Category
- Article
- ISSN
- 0007-0963
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Drug-induced hypersensitivity syndrome (DIHS), characterized by serious adverse systemic reactions in addition to skin rash, has unknown pathogenesis. Its association with human herpesvirus (HHV), mainly HHV-6, has been reported recently. A 46-year-old Japanese man is described in whom a generalized
## Abstract It has been suggested that immunosuppression associated with human herpesvirus 6 (HHVโ6) infection is a result of functional impairment or direct destruction of immunological cells. The ability of the virus to infect and destroy lymphocytes may cause progressive immunodeficiency in an i