Association of glutathione S-transferase omega gene polymorphisms with progression of head and neck cancer
β Scribed by S. Sanguansin, S. Petmitr, P. O-charoenrat, W. Pongstaporn
- Book ID
- 120751234
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 185 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0301-4851
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## Abstract ## Background. Factors determining the individual susceptibility to head and neck squamous cell carcinoma (HNSCC) are still largely unknown. An imbalance between enzymes involved in the toxification and detoxification of (pre)βcarcinogens closely related to HNSCC, which may appear duri
Differences in genetic susceptibility to tobacco-induced carcinogenesis appear to modulate an individual's risk of squamous-cell carcinoma of the head and neck (SCCHN). Risk for SCCHN may be associated with the null alleles of the carcinogen-metabolizing genes glutathione-S-transferase (GST) T1 and