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Association of Crohn’s Disease, Thiopurines, and Primary Epstein-Barr Virus Infection with Hemophagocytic Lymphohistiocytosis

✍ Scribed by Vincent F. Biank; Mehul K. Sheth; Julie Talano; David Margolis; Pippa Simpson; Subra Kugathasan; Michael Stephens


Book ID
113746703
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
125 KB
Volume
159
Category
Article
ISSN
1097-6833

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## BACKGROUND. Although familial hemophagocytic lymphohistiocytosis (FHL) has been considered a T-cell disorder, to the authors' knowledge there are no previous reports on the clonal basis of FHL. In the current study the authors analyzed the clonality of T-cells in two FHL patients at the time of