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Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases

✍ Scribed by Mamtani, M; Anaya, J-M; He, W; Ahuja, S K


Book ID
109852944
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
229 KB
Volume
11
Category
Article
ISSN
1466-4879

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The FCGR locus encoding the low-affinity FcΞ³ receptors (FcΞ³R) for immunoglobulin G has largely been missed by genome-wide association studies due to complications with structural variation and segmental duplication. Recently identified copy number variants (CNVs) affecting FCGR3A and FCGR3B have bee