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FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

โœ Scribed by Fanciulli, Manuela; Norsworthy, Penny J; Petretto, Enrico; Dong, Rong; Harper, Lorraine; Kamesh, Lavanya; Heward, Joanne M; Gough, Stephen C L; de Smith, Adam; Blakemore, Alexandra I F


Book ID
109919567
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
138 KB
Volume
39
Category
Article
ISSN
1061-4036

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Confirmation of association of FCGR3B bu
โœ James I. Robinson; Ian M. Carr; Dawn L. Cooper; Lubna H. Rashid; Stephen G. Mart ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 352 KB

The FCGR locus encoding the low-affinity Fcฮณ receptors (FcฮณR) for immunoglobulin G has largely been missed by genome-wide association studies due to complications with structural variation and segmental duplication. Recently identified copy number variants (CNVs) affecting FCGR3A and FCGR3B have bee