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Association of class II MHC restriction fragment length polymorphisms (RFLPs) with seropositive rheumatoid arthritis (RA)


Book ID
123126404
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
78 KB
Volume
17
Category
Article
ISSN
0198-8859

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We analyzed DNA restriction fragment length polymorphism (RFLP) in 53 white ankylosing spondylitis (AS) patients and 92 healthy controls, utilizing a full-length HLA-B7 complementary DNA probe. A 9.2kilobase (kb) Pvu I1 fragment was found to be significantly increasexn frequency in B27 positive AS p