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Association of cholecystokinin-A receptor gene polymorphism and the symptoms of schizophrenia

โœ Scribed by X.Y. Zhang; D.F. Zhou; J. Wei

Book ID
119554051
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
200 KB
Volume
41
Category
Article
ISSN
0920-9964

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โœ Tachikawa, Hirokazu; Harada, Shoji; Kawanishi, Yoichi; Okubo, Takehito; Shiraish ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 15 KB ๐Ÿ‘ 3 views

The cholecystokinin A receptor (CCK-AR) modulates CCK-stimulated dopamine release in the posterior nucleus accumbens, and its gene is mapped to 4p15.2-15.1 with the dopamine receptor 5 (DR5) gene. We speculated that alterations in the CCK-AR lead to an increase in dopamine release, which may in turn