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Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

✍ Scribed by Ralph Scully; Junjie Chen; Annemieke Plug; Yonghong Xiao; David Weaver; Jean Feunteun; Terry Ashley; David M Livingston

Book ID: 117268559
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 383 KB
Volume: 88
Category: Article
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81847-4

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BACKGROUND. BRCA1 and BRCA2 participate in cell cycle progression, apoptosis, and DNA repair pathways. The latter role may be mediated by interaction with DNA recombinase Rad51. The purpose of this study was to evaluate the effects of genotoxic and other cytotoxic agents on expression of DNA damage-