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Association of a functional polymorphism in the 3′-untranslated region of SPI1 with systemic lupus erythematosus

✍ Scribed by Koki Hikami; Aya Kawasaki; Ikue Ito; Minori Koga; Satoshi Ito; Taichi Hayashi; Isao Matsumoto; Akito Tsutsumi; Makio Kusaoi; Yoshinari Takasaki; Hiroshi Hashimoto; Tadao Arinami; Takayuki Sumida; Naoyuki Tsuchiya


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
189 KB
Volume
63
Category
Article
ISSN
0004-3591

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Functional effects of genetic polymorphi
✍ Yuanqi Zhu; J. Christopher States; Yang Wang; David W. Hein 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB

The functional effects of N-acetyltransferase 1 (NAT1) polymorphisms and haplotypes are poorly understood, compromising the validity of associations reported with diseases, including birth defects and numerous cancers. METHODS: We investigated the effects of genetic polymorphisms within the NAT1 cod