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Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains

✍ Scribed by A. V. Kulikov; D. V. Osipova; V. S. Naumenko; N. K. Popova

Book ID
111272967
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
514 KB
Volume
4
Category
Article
ISSN
1601-1848

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## Abstract Tryptophan hydroxylase‐2 (TPH2) is the rate‐limiting enzyme of brain serotonin synthesis. The C1473G polymorphism in the mouse tryptophan hydroxylase‐2 gene affects the enzyme's activity. In the present study, we investigated the linkage between the C1473G polymorphism, enzyme activity