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Association between the α-adducin gene and hypertension in the HyperGEN study

✍ Scribed by Michael A Province; Donna K Arnett; Steven C Hunt; Cathie Leiendecker-Foster; John H Eckfeldt; Albert Oberman; R.Curtis Ellison; Gerardo Heiss; Stephen C Mockrin; Roger R Williams


Book ID
117605330
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
203 KB
Volume
13
Category
Article
ISSN
0895-7061

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Association between hypertension and var
✍ Wang, Ji-Guang; Staessen, Jan A.; Barlassina, Cristina; Fagard, Robert; Kuznetso 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 119 KB

## Background: The substitution of tryptophan for glycine at amino acid 460 (gly460trp polymorphism) of the alpha-subunit of the heterodimeric cytoskeleton protein adducin increases renal sodium reabsorption and may be involved in the pathophysiology of essential hypertension. in the present study,