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Association between the PI*M3 allele of α1-antitrypsin and Alzheimer’s disease? A preliminary report

✍ Scribed by A. Kowalska; Heidi Danker-Hopfe; Mieczyslaw Wender; Jolanta Florczak; Hubert Walter


Publisher
Springer
Year
1996
Tongue
English
Weight
38 KB
Volume
98
Category
Article
ISSN
0340-6717

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A common polymorphism in the α1-antichymotrypsin (ACT) gene has been found to modify the APOE\*4-associated risk of Alzheimer's disease due to an apparent interaction between the two loci. This study was undertaken to determine the gender-and age-related distributions of these two polymorphisms in t