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Association between schizophrenia and the dopamine receptor DRD4

✍ Scribed by Macciardi, F.; Verga, M.; Kennedy, J.L.; Cavallini, M.C.; Catalano, M.; Smeraldi, E.


Book ID
123211280
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
165 KB
Volume
4
Category
Article
ISSN
0924-977X

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The dopamine D4 receptor is of major interest in schizophrenia research due to its high affinity for the atypical neuroleptic clozapine and a high degree of variability in the receptor gene (DRD4). Although several genetic linkage analyses performed on schizophrenia multiplex families from different