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Association between schizophrenia and DRD3 or HTR2 receptor gene variants

✍ Scribed by Baritaki, S; Rizos, E; Zafiropoulos, A; Soufla, G; Katsafouros, K; Gourvas, V; Spandidos, D A


Book ID
110025587
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
112 KB
Volume
12
Category
Article
ISSN
1018-4813

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## A missense polymorphism (glycine to serine) in the first exon of the dopamine D3 (DRD3) gene was examined in a sib-pairs schizophrenia collection by the transmission test for linkage disequilibrium (TDT). No association due to linkage disequilibrium was detected using TDT. Additionally, no evide

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reported identifying one missense nucleotide mutation from C to G resulting in a substitution of serine with cysteine at codon 311 in the third intracellular loop of the dopamine D2 receptor in schizophrenics. Arinami et al. 119941 reported finding a positive association between the Cys311 variant a