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Association Between MDM2-SNP309 and Age at Colorectal Cancer Diagnosis According to p53 Mutation Status

โœ Scribed by Menin, C.; Scaini, M. C.; De Salvo, G. L.; Biscuola, M.; Quaggio, M.; Esposito, G.; Belluco, C.; Montagna, M.; Agata, S.; D'Andrea, E.; Nitti, D.; Amadori, A.; Bertorelle, R.

Book ID
125538363
Publisher
Oxford University Press
Year
2006
Tongue
English
Weight
184 KB
Volume
98
Category
Article
ISSN
0027-8874

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MDM2 SNP309 T>G alone or in combination
MDM2 SNP309 T>G alone or in combination with the TP53 R72P polymorphism does not appear to influence disease expression and age of diagnosis of colorectal cancer in HNPCC patients
โœ Bente A. Talseth; Cliff Meldrum; Janina Suchy; Grzegroz Kurzawski; Jan Lubinski; ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 64 KB ๐Ÿ‘ 1 views

## Abstract Disease expression in hereditary nonpolyposis colorectal cancer (HNPCC) cannot be readily explained by mutation site in the respective DNA mismatch repair genes associated with this disorder. One explanation is the role of modifying genes that can either promote or prevent disease devel