Association between insulin-like growth factor-1 polymorphisms and stomach cancer risk in a Japanese population
β Scribed by Daisuke Ennishi; Kohei Shitara; Hidemi Ito; Satoyo Hosono; Miki Watanabe; Seiji Ito; Akira Sawaki; Yasushi Yatabe; Kenji Yamao; Kazuo Tajima; Mitsune Tanimoto; Hideo Tanaka; Nobuyuki Hamajima; Keitaro Matsuo
- Book ID
- 108589155
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 127 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1347-9032
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In the current study the authors have investigated whether human primary breast cancer specimens contain insulin-like growth factor-1 (IGF-1) receptors (IGF-1-R) or IGF-1-like activities. Simultaneously, epidermal growth factor (EGF) receptors (EGF-R) and cytosolic estrogen receptor (ER), progestero
## Abstract The evidence that high circulating levels of insulinβlike growth factorβI (IGFβI) are associated with an increased risk of breast cancer among premenopausal women lends credence to the hypothesis that genetic polymorphisms in the __IGFβI__ gene may be involved in the disease. A populati