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Association between gene alteration and drug sensitivity in human lung carcinoma cell lines

Book ID
123466496
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
126 KB
Volume
13
Category
Article
ISSN
0169-5002

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Aberrant proteins encoded from genes altered in tumors drive cancer development and may also be therapeutic targets. Here we derived a comprehensive gene-alteration profile of lung cancer cell lines. We tested 17 genes in a panel of 88 lung cancer cell lines and found the rates of alteration to be h