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Analysis of β-tubulin gene alteration in human lung cancer cell lines

✍ Scribed by Hiroyuki Achiwa; Shigeki Sato; Shigeki Shimizu; Hiroyoshi Maeda; Takashi Niimi; Takashi Takahashi; Ryuzo Ueda; Tetsuya Mitsudomi

Book ID
117467961
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
219 KB
Volume
201
Category
Article
ISSN
0304-3835

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Aberrant proteins encoded from genes altered in tumors drive cancer development and may also be therapeutic targets. Here we derived a comprehensive gene-alteration profile of lung cancer cell lines. We tested 17 genes in a panel of 88 lung cancer cell lines and found the rates of alteration to be h