Association between cell swelling and glycogen content in cultured astrocytes
โ Scribed by Roy S Dombro; Alex S Bender; Michael D Norenberg
- Book ID
- 117563979
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 278 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0736-5748
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๐ SIMILAR VOLUMES
Ammonia is the principal neurotoxin implicated in the pathogenesis of hepatic encephalopathy, and astrocytes are the neural cells predominantly affected in this condition. Astrocyte swelling (cytotoxic edema) represents a critical component of the brain edema in acute form of hepatic encephalopathy
Cytotoxic brain edema, usually a consequence of astrocyte swelling, is an important complication of stroke, traumatic brain injury, hepatic encephalopathy, and other neurological disorders. Although mechanisms underlying astrocyte swelling are not fully understood, oxidative stress (OS) has generall