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Association analysis of lipid levels and apolipoprotein restriction fragment length polymorphisms

✍ Scribed by Ola Myklebost; Sissel Rogne; Ingvar Hjermann; Bjørnar Olaisen; Hans Prydz

Publisher
Springer
Year
1990
Tongue
English
Weight
623 KB
Volume
86
Category
Article
ISSN
0340-6717

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✦ Synopsis

We have analyzed the correlation between restriction site variants (RFLPs; restriction fragment length polymorphisms) of the apolipoprotein AI, AII, B, CI and CII genes and serum lipid levels in a sample of male Norwegians. We find no significant association between any of the RFLPs and lipid levels.

probes to analyze whether apolipoprotein RFLPs may be associated with abnormal lipid levels. This work is part of a long term prospective study of phenotypic and genetic risk factors for CVD in Norwegian men (Leren et al. 1975; S. Rogne, O. Myklebost, P. Smith, J. Hjermann, B. Olaisen, and H. Prydz, unpublished work).

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