Association analysis of ATF4 and ATF5, genes for interacting-proteins of DISC1, in bipolar disorder
โ Scribed by Chihiro Kakiuchi; Mizuho Ishiwata; Shinichiro Nanko; Hiroshi Kunugi; Yoshio Minabe; Kazuhiko Nakamura; Norio Mori; Kumiko Fujii; Kazuo Yamada; Takeo Yoshikawa; Tadafumi Kato
- Book ID
- 116769454
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 528 KB
- Volume
- 417
- Category
- Article
- ISSN
- 0304-3940
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We selected 42 patients with bipolar disorder type I (BPI) and 40 healthy controls for genetic analysis of DNA polymorphisms in the serotonin receptor 2c (5-HTR2c) and serotonin transporter (5-HTT) genes. No significant associations were found in the total patient sample. However, when the individua
## Abstract DisruptedโinโSchizophrenia 1 (DISC1) and its molecular cascade have been implicated in the pathophysiology of major psychoses. Previously, we identified pericentrin 2 (PCNT2) and DISC1โbinding zinc finger protein (DBZ) as binding partners of DISC1; further, we observed elevated expressi