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Association analyses of DNA methyltransferase-1 (DNMT1) polymorphisms with systemic lupus erythematosus

✍ Scribed by Byung Lae Park; Lyoung Hyo Kim; Hyoung Doo Shin; Yong Wook Park; Wan Sik Uhm; Sang-Cheol Bae

Book ID
106251828
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
239 KB
Volume
49
Category
Article
ISSN
1435-232X

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An osteopontin (SPP1) polymorphism is as
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Osteopontin (SPP1) is a soluble ligand with pleomorphic immunologic activities including activation of macrophage chemotaxis, promotion of Th1 responses, and activation of B1 B cells. It has been implicated in the development of murine lupus and is overexpressed in humans with systemic lupus erythem