Assignments of 1H and 13C NMR spectral data for ondansetron and its two novel metabolites, 1-hydroxy-ondansetron diastereoisomers
✍ Scribed by Mingyu Duan; Haihua Huang; Xinnan Li; Xiaoyan Chen; Dafang Zhong
- Book ID
- 102525697
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 150 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.1876
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Assignments of ^1^H and ^13^C NMR chemical shifts were made by means of heteronuclear single quantum coherence (HSQC) and heteronuclear multiple bond correlation (HMBC) experiments for ondansetron, and by means of ^1^H‐^1^H correlation spectroscopy (^1^H‐^1^H COSY) and two‐dimensional nuclear Overhauser effect spectroscopy (NOESY) experiments for two novel metabolites (M1 and M2) of ondansetron. These two metabolites were isolated for the first time from Mucor circinelloides. Copyright © 2006 John Wiley & Sons, Ltd.
📜 SIMILAR VOLUMES
## Abstract In this work we describe the complete ^1^H and ^13^C NMR analyses of three arylnaphtalene lignan lactones (taiwanin C, 4‐methyl dehydroretrodendrin and justicidin B) using modern NMR techniques such as gCOSY, nonedited gHSQC, gHMBC and NOE experiments. Complete assignment and homonuclea
## Abstract The structures of three benzylidenebenzyl butyrolactone lignans (gossypifan, carthamogenin, and savinin) have been established on basis of ^1^H NMR and ^13^C NMR spectroscopic data. The ^1^H NMR and ^13^C NMR spectra of these lignans have been fully assigned by the use of techniques suc
## Abstract Semiaquilegoside A (1), a new diterpenoid, was isolated from the roots of __Semiaquilegia adoxoides__. Its chemical structure was established as 3β, 11‐ dihydroxy‐12‐__O__‐β‐D‐glucopyranosyl‐8,11,13‐abietatrien‐6‐one through spectroscopic techniques and chemical analysis. Copyright © 20
## Abstract The anabaseine derivatives 6‐methoxy‐7‐hydroxy‐1‐(pyridin‐3‐yl)‐3,4‐dihydroisoquinoline, 6,7‐dimethoxy‐1‐(pyridin‐3‐yl)‐1,2,3,4‐tetrahydroisoquinoline and 6,7‐dimethoxy‐1‐(piperidin‐3‐yl)‐1,2,3,4‐tetrahydroisoquino‐ line were prepared either by demethylation with HBr or by reduction wit