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Assignment of the Human GDID4 Gene, a GDP/GTP-Exchange Regulator, to Chromosome 12p12.3

✍ Scribed by Chaker N. Adra; Hirofumi Kobayashi; Janet D. Rowley; Bing Lim

Book ID
115612447
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
149 KB
Volume
24
Category
Article
ISSN
0888-7543

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Localization of the CDKN4/p27Kip1gene to
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CDKN4/p27Kip1 is a cyclin-dependent kinase (Cdk) inhibitor implicated in G1 phase arrest, which negatively regulates G1 phase progression in response to TGF beta, and might represent a tumor suppressor gene. We report here the chromosomal assignment of the human CDKN4 gene to chromosome 12p12.3 in c