Fusidic acid inhibits prokaryotic protein biosynthesis in viuo and in vitro' by binding to elongation factor G (EF-G). EF-G catalyses the translocation step of peptide elongation by forming a complex with GTP and the ribosome. Translocation takes place with GTP hydrolysis and EF-G.GDP leaves the rib
Assignment of the 13c nmr spectra of fusidic acid derivatives. Biosynthetic incorporation of sodium [1-13c]-acetate into fusidic acid
β Scribed by T. Riisom; H.J. Jakobsen; N. Rastrup-Andersen; H. Lorck
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 254 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Fusidic acid (I) (l-5), a useful antibiotic in the treatment of staphylococcal infections in man, differs from the androstane and cholestane steroids
π SIMILAR VOLUMES
## Abstract Reassignment of the ^1^H and ^13^C NMR spectra of fusidic acid and the total assignment of lumifusidic acid and some important diβ and tetraβhydrofusidic acid derivatives are reported. Copyright Β© 2002 John Wiley & Sons, Ltd.
We report the use of doubly labelled acetate and FT-'aC-NMR in the determination of the biosynthetic origin of ovalicin (1) (1) (graphinone),a sesquiterpene found in cultures of Pseudeurotium ovalis. The fungus was cultured in media fortified with 90% enriched 1,2-i3C-acetate that was diluted two-f
## Abstract The complete assignment of the ^1^H and ^13^C spectra of 2β__exo__β and 2β__endo__βnorβbornenemethanol is presented. Resonance assignment was achieved using ^1^Hβ^1^H double resonance, COSY and ^1^H/^13^C correlation spectra. Computer simulations of the Hβ2 (__exo__ or __endo__) proton