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Assessment of the mutagenic potential of arecoline in gpt delta transgenic mice

✍ Scribed by Mengjun Wu; Guozhen Xing; Xinming Qi; Chenchen Feng; Mingxia Liu; Likun Gong; Yang Luan; Jin Ren

Book ID
119330399
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
202 KB
Volume
748
Category
Article
ISSN
1383-5718

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Ultraviolet light B (UVB)-induced mutagenesis was studied in gpt delta transgenic mice, which contain the EG10 shuttle vector as a transgene. The mice were exposed to UVB at single doses of 0.3, 0.5, 1.0, 1.5, and 2.0 kJ/m 2 . At 4 weeks after irradiation, the mutant frequencies (MF) of the gpt gene