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Assessment of the genotoxic risk from laxative senna products

✍ Scribed by David Brusick; Ulrich Mengs

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 97 KB
Volume: 29
Category: Article
ISSN: 0893-6692
DOI: 10.1002/(sici)1098-2280(1997)29:1<1::aid-em1>3.0.co;2-j

No coin nor oath required. For personal study only.

✦ Synopsis

Laxative senna products and several of their specific stances, in light of other data from animal and hucomponents have been submitted to a large number man metabolism or kinetic studies, human clinical of genetic tests. While most studies gave negative trials and rodent carcinogenicity studies do not supresponses, results from some of the studies suggest port concerns that senna laxatives pose a genotoxic that components of senna products, particularly em-risk to humans when consumed under prescribed odin and aloe-emodin, have genotoxic activity. As-use conditions.

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